Absorption of Di- and triglycerides by intestinal slices in vitro |
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Authors: | Elaine Bossak Feldman Bengt Borgström |
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Affiliation: | (1) Department of Physiological Chemistry, University of Lund, Lund, Sweden;(2) Present address: Department of Medicine, State University of New York Downstate Medical Center, Brooklyn, N.Y. |
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Abstract: | The uptake by hamster intestinal rings of labeled 1,3-diolein and triolein in bile salt emulsions was studied.
About 6% of triolein was taken up from emulsions containing glycerides and fatty acid in 6 mM sodium taurodeoxycholate. Lesser
uptake was noted when triolein was emulsified with lecithin, cholesterol and bile salt; lowest uptake (3%) was observed from
triolein-lecithincholesterol emulsions prepared without bile salt.
Absorption of 1,3-diolein from bile salt emulsion was greater and acylation to triglyceride was observed.
Diglycerides and triglycerides in small quantity may be absorbed intact from a micellar phase. |
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