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Synthesis and characterization of core-shell hydroxyapatite/chitosan biocomposite nanospheres
Authors:Xiangnan Li  Xiaoming Chen  Shipu Li  Zhiming Peng
Affiliation:(1) Department of Mechanical Engineering, The University of Hong Kong, Pokfulam Road, Hong Kong, Hong Kong, China;(2) Department of Polymer Materials and Engineering, South China University of Technology, Guangzhou, 510640, China;
Abstract:Novel core-shell hydroxyapatite/chitosan biocomposite nanospheres were synthesized in a multiple emulsion. The multiple emulsion was a w/o/w emulsion, made of diammonium phosphate solution as an inner aqueous phase, cyclohexane as an oil phase, and calcium nitrate solution and chitosan solution as an outer aqueous. The forming mechanism of core-shell spheres and the influence of temperature on the morphology of the nanospheres were investigated. The diameter of the resulting core-shell nanospheres was 100–200 nm and the thickness of the chitosan shell was about 10 nm. And it concluded that at different reaction temperature the morphologies of the products would be changed. The core-shell nanospheres have potential applications for the development of new biomedical materials.
Keywords:
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