Polymorphism and expression of the porcine Tenascin C gene associated with meat and carcass quality |
| |
Authors: | Kayan A Cinar M U Uddin M J Phatsara C Wimmers K Ponsuksili S Tesfaye D Looft C Juengst H Tholen E Schellander K |
| |
Affiliation: | Institute of Animal Science, Animal Breeding and Husbandry Group, University of Bonn, 53115 Bonn, Germany. akay@itw.uni-bonn.de |
| |
Abstract: | The research aimed to screen for polymorphism, expression of Tenascin C (TNC) and association with meat and carcass quality traits. Three single nucleotide polymorphisms were detected. In a Duroc×Pietrain F2 cross (DuPi) population, g.44488C>T was associated with meat color and ham weight; g.68794A>G was associated with pH at 24h post mortem in ham (pH24(H)) and muscle area but g.68841C>T was not statistically associated. Genotyping in a commercial Pietrain (Pi) population showed that g.44488C>T was associated with pH24(H), whereas g.68794A>G was associated with conductivity at 45 min post mortem in loin and backfat thickness. Diplotypes showed significant effects on pH24(H) in both populations. The expression was associated with pH at 45 min post mortem in loin and cooking loss. TNC was significantly higher in animals with higher muscle pH. Linkage analysis revealed four trans-regulated eQTL on four autosomes. These results suggest that TNC could be a potential candidate gene for meat quality traits in pigs. |
| |
Keywords: | TNC gene Single nucleotide polymorphism mRNA expression Association eQTL Meat and carcass quality |
本文献已被 ScienceDirect PubMed 等数据库收录! |