生物活性肽的研究进展理论基础与展望

随着具各种生物活性的短肽的不断发现，其研究和开发日益受到各国科学家的关注。大量科学研究表明，通过选择适当的蛋白酶，水解的蛋白质可以得到大量的具有各种生物功能的生物活性肽，这些活性肽不仅具有极其广泛的活性和多样性，而且其来源丰富、成本低、安全性好。操作简单、便于工业化生产，因此已成为科学家们研究的新热点。例如：酪蛋白是哺乳动物乳中含量最丰富的蛋白质，长期以来，被人们视为一种营养蛋白，但近年来的研究结果表明，它是生物活性肽的重要来源，到目前为止，已经有数十种生物活性肽被水解和辨认出来。所以，生物活性肽非常好的研究与开发前景。

Review on thcorctical Principle Progress and Prospect of Bioactive Pcptidcs

When more and more new kinds of bioactive peptides were discovered, the studying area for bioactive peptides became a focus of attention in many countries. Many research works have shown that a large number of bioactive peptides could be found when some kinds of rich proteins could be hydrolyzed by proper proteinase. These peptides not only had various biological functions and sequence diversity but they were also easy to get with abundant resoucces , lower cost and safely, conveniently to scale up, so it has attracted many scientists attentions. As a good example, casein has been of rich protein in mammal milk. For a long time, milk proteins particularly casein, have been considered as only food proteins for young mammals. Casein was also the principal source of amino acid for young animals. But besides the nutritional role, casein had also a physiological importance,i.e., it was the important source of bioactive peptides. Many kinds of bioactive peptides have been discovered from hydrolyzed casein. So it would be very important and of good prospects to do more research works on this area.