| 丙烯酸酯类毛细管液相色谱整体柱的制备与评价 |
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| 引用本文： | 张军霞,陈娜,杨胜凯,杨占君,张裕平. 丙烯酸酯类毛细管液相色谱整体柱的制备与评价[J]. 生命科学仪器, 2009, 7(7) |
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| 作者姓名： | 张军霞 陈娜 杨胜凯 杨占君 张裕平 |
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| 作者单位： | 张军霞(河南省药检所,河南,郑州,450003;河南科技学院,河南,新乡,453003);陈娜,杨胜凯,杨占君,张裕平(河南科技学院,河南,新乡,453003) |
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| 基金项目： | 教育部归国留学人员科研启动项目、河南省高校新世纪优秀人才项目，高校骨干教师项目资助 |
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| 摘 要： | 采用甲基丙烯酸丁酯(BMA)为功能单体,己二醇二甲基丙烯酸酯(EDMA)为交联剂,正丙醇、1,4-丁二醇和水为致孔剂,偶氮二异丁腈(AIBN)为引发剂,采用微波辐射的新方法,在毛细管内原位聚合快速制备了毛细管整体柱。扫描电镜结果表明整体材料在毛细管柱中均匀形成并与毛细管内壁结合紧密。采用自组装的毛细管液相色谱仪,优化条件下可实现了模型化合物的基线分离。与传统的热聚合和光聚合相比,微波辐射用于有机聚合基质毛细管整体柱的制备是一种更快捷、简单、有效的方法。
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| 关 键 词： | 微波辐射 整体柱 毛细管液相色谱 甲基丙烯酸丁酯 |
Preparation and Evaluation of Methacrylate-based Monolithic Column for Capillary Liquid Chromatography |
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| Jun-Xia Zhang,;,; Na Chen,; Sheng-Kai Yang,; Zhan-Jun Yang,; Yu-Ping Zhang. Preparation and Evaluation of Methacrylate-based Monolithic Column for Capillary Liquid Chromatography[J]. Life Science Instruments, 2009, 7(7) |
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| Authors: | Jun-Xia Zhang, , Na Chen, Sheng-Kai Yang, Zhan-Jun Yang, Yu-Ping Zhang |
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| Affiliation: | 1. Henan Provincial Institute of Food and Drug Control; Zhengzhou 450003; China; 2. Henan Institute of Science and Technology; Xinxiang 453003; China ); |
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| Abstract: | A methacrylate-based monolith was fabricated inside the fused-silica capillary, which in situ polymerization was rapidly carried out by microwave irradiation. The reactant solution was consisted of butyl-methacrylate (BMA) as a functional monomer, ethylene glycol dimethacrylate (EDMA) as a cross-linking agent, 1-propanol, 1,4-butanediol and water as porogenic solvents and azobisisobutyronitrile (AIBN) as an initiator. The chromatographic performance of the prepared stationary phases was evaluated using the ... |
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| Keywords: | Microwave irradiation monolithic column Capillary liquid chromatography Methacrylate |
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