Detection of drugs of abuse in saliva by surface-enhanced Raman spectroscopy (SERS) |
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| Authors: | Inscore Frank Shende Chetan Sengupta Atanu Huang Hermes Farquharson Stuart |
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| Affiliation: | Real-Time Analyzers, Inc., 362 Industrial Park Rd #8, Middletown, Connecticut 06457, USA. |
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| Abstract: | Eighty drugs of abuse and metabolites were successfully measured by surface-enhanced Raman spectroscopy (SERS) using gold- and silver-doped sol-gels immobilized in glass capillaries. A method was developed that provided consistent detection of 50 ppb cocaine in saliva in a focused study. This general method was successfully applied to the detection of a number of additional drugs in saliva, such as amphetamine, diazepam, and methadone. |
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