| 双环中同时被取代的异色满类化合物合成研究 |
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| 引用本文： | 牛治刚,韩波,韩腾.双环中同时被取代的异色满类化合物合成研究[J].四川化工,2013(5):20-23. |
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| 作者姓名： | 牛治刚 韩波 韩腾 |
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| 作者单位： | [1]兰州石化职业技术学院应用化学工程系,甘肃兰州730060 [2]兰州石化公司催化剂厂,甘肃兰州730060 [3]兰州路博润兰炼添加剂有限公司,甘肃兰州730060 |
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| 摘 要： | 双环中同时被取代的许多异色满化合物具有广泛的生物活性,其中包括抗抑郁、抗炎、降压、利尿和抗癌等药用功能。综述了苯环和二氢吡喃环中同时被取代的异色满化合物类化合物合成的常用方法,通过各种方法的对比得出,水溶液中环化反应更具有广泛的应用价值。
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| 关 键 词： | 异色满 合成 研究 |
Study on Synthesis of Isochroman with Substituents in Rings |
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| Niu Zhigang Han Bo Han Teng.Study on Synthesis of Isochroman with Substituents in Rings[J].sichuan chemical industry,2013(5):20-23. |
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| Authors: | Niu Zhigang Han Bo Han Teng |
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| Affiliation: | Niu Zhigang Han Bo Han Teng(1. Department of Applied Chemistry Engineering, Lanzhou Petrochemical College of Technology, Lanzhou 730060, Gansu, China2. Lan zhou Petrochemical Company Catalyst factory ,Gansu Lanzhou 730060, Gansu, China; 3. Department of Marketing and transportation of Additives Limited Company o fLu Borun Lanlian , Lanzhou 730060, Gansu,China) |
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| Abstract: | Derivatives of isochroman with substituents in the aromatic and dihydropyran rings are all characterised by a broad spectrum of biological activity： anti-depressant, antiinflammatory, antihypertensive,diuretic, anticancer. The paper mainly review the synthesis of isochroman with substituents in in the aromatic and dihydropyran rings. Through the comparison of various methods, the cyclisation reaction in aqueous solutions has more extensive application. |
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| Keywords: | isochroman synthesis study |
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