| 含氮黄酮类衍生物的合成研究进展 |
| |
| 引用本文： | 肖咏梅,杨亮茹,毛璞,栗俊田,袁金伟,屈凌波. 含氮黄酮类衍生物的合成研究进展[J]. 河南工业大学学报(自然科学版), 2012, 33(2): 83-88,94 |
| |
| 作者姓名： | 肖咏梅 杨亮茹 毛璞 栗俊田 袁金伟 屈凌波 |
| |
| 作者单位： | 河南工业大学化学化工学院,河南郑州,450001 |
| |
| 基金项目： | 河南省科技攻关项目(82102330014);郑州市科技局攻关项目(2010GYXM639) |
| |
| 摘 要： | 黄酮类化合物不仅是一种天然的食品添加剂,而且具有抗氧化、抗菌、抗癌等活性.但因大部分天然黄酮的脂溶性或水溶性较差,致使其生物利用度较低.引入含氮基团,可有效地提高其药理活性和溶解性.综述了含氮黄酮类化合物合成的新进展.
|
| 关 键 词： | 黄酮类化合物 含氮衍生物 活性 |
PROGRESS ON SYNTHESIS OF NITROGEN-CONTAINING FLAVONOID DERIVATIVES |
| |
| XIAO Yong-mei , YANG Liang-ru , MAO Pu , LI Jun-tian , YUAN Jin-wei , QU Ling-bo. PROGRESS ON SYNTHESIS OF NITROGEN-CONTAINING FLAVONOID DERIVATIVES[J]. Journal of Henan University of Technology Natural Science Edition, 2012, 33(2): 83-88,94 |
| |
| Authors: | XIAO Yong-mei YANG Liang-ru MAO Pu LI Jun-tian YUAN Jin-wei QU Ling-bo |
| |
| Affiliation: | (School of Chemistry & Chemical Engineering,Henan University of Technology,Zhengzhou 450001,China) |
| |
| Abstract: | Flavonoids are natural food additives and have antioxidant,antibacterial and anti-cancer activities and so on.However,the majority of natural flavonoids have low bioavailability because of the poor lipid solubility or water solubility.The introduction of nitrogen-containing groups can effectively improve the solubility and pharmacological activity of flavonoids.The paper summarized the progress on the synthesis of nitrogen-containing flavonoid derivatives. |
| |
| Keywords: | flavonoids nitrogen-containing derivative activity |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
|
