色谱质谱技术在食品安全分析检测中的应用

食品安全是关系国计民生的重要议题。准确、深入、高效的食品安全分析检测技术是防控食品安全事件发生及处理相关贸易纠纷、立法追责的基础和保障。色谱质谱技术作为高效的分离和检测手段是目前食品安全分析领域最重要、最主流的技术手段。近年来,色谱质谱领域的新发展也推动了食品安全分析检测向更快速,更有效,更可靠,更安全的目标迈进,本综述就其中最重要并有望代表未来食品安全分析发展趋势的色谱质谱技术做了总结和点评。如用于食品样品预处理的固相微萃取技术;气相色谱及气相色谱质谱联用技术中的快速气相色谱方法及其与质谱联用方法,二维气相色谱方法及其与质谱联用方法;液相色谱及液相色谱质谱联用技术中的超高效液相色谱及其与质谱联用方法,毛细管液相色谱和纳流液相色谱及其与质谱联用方法,超临界色谱及其与质谱联用方法,二维液相色谱及其与质谱联用方法;质谱分析技术中的超高分辨率质谱方法,常压敞开式离子源质谱技术等。

Application of chromatography and mass spectrometry in food safety analysis

Food quality and safety have become one of the most concerns in recent years. Demand for the development and the applications of more efficient and more powerful tools to analyze food components and food contaminants have significantly increased. Chromatography and mass spectrometry are such tools that play major roles in food safety analysis. This review described the application of technology advances of chromatography and mass spectrometry in analysis of known and unknown compounds in food matrix. The summarized development included solid phase microextraction, high speed gas chromatography and its combination with mass spectrometry, two-dimensional gas chromatography and its combination with mass spectrometry, ultra-high pressure liquid chromatography and its combination with mass spectrometry, capillary-liquid chromatography and nano-liquid chromatography and their combination with mass spectrometry, supercritical fluid chromatography and its combination with mass spectrometry, two-dimensional liquid chromatography and its combination with mass spectrometry, high-resolution mass spectrometry and ambient mass spectrometry.