Redox Capacitor to Establish Bio‐Device Redox‐Connectivity |
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Authors: | Eunkyoung Kim Yi Liu William E. Bentley Gregory F. Payne |
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Affiliation: | Institute for Bioscience and Biotechnology Research and Fischell Department of Bioengineering, 5115 Plant Sciences Buildin, University of Maryland, College Park, MD 20742, USA |
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Abstract: | Electronic devices process information and transduce energy with electrons, while biology performs such operations with ions and chemicals. To establish bio‐device connectivity, we fabricate a redox‐capacitor film from a polysaccharide (i.e., chitosan) and a redox‐active catechol. We report that these films are rapidly and repeatedly charged and discharged electrochemically via a redox‐cycling mechanism in which mediators shuttle electrons between the electrode and film (capacitance ≈ 40 F/g or 2.9 mF/cm2). Further, charging and discharging can be executed under bio‐relevant conditions. Enzymatic‐charging is achieved by electron‐transfer from glucose to the film via an NADPH‐mediated redox‐cycling mechanism. Discharging occurs by electron‐donation to O2 to generate H2O2 that serves as substrate for peroxidase‐mediated biochemical reactions. Thus, these films offer the capability of inter‐converting electrochemical and biochemical inputs/outputs. Among potential applications, we anticipate that catechol–chitosan redox‐capacitor films could serve as circuit elements for molecular logic operations or for transducing bio‐based chemical energy into electricity. |
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Keywords: | catechol chitosan glucose dehydrogenase reactive oxygen species redox capacitor |
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