| 吡虫啉相关化合物的合成及其杀虫效能 |
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| 引用本文： | 莫羡忠,陈文纳,潘英明,张巧平,崔建国,文小玲.吡虫啉相关化合物的合成及其杀虫效能[J].精细化工,2000,17(8):447-449. |
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| 作者姓名： | 莫羡忠 陈文纳 潘英明 张巧平 崔建国 文小玲 |
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| 作者单位： | 广西师范学院,应用化学研究所,广西,南宁,530001 |
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| 基金项目： | 广西科技厅青年科学基金!资助项目 (桂科青 9753 0 1 9) |
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| 摘 要： | 吡虫啉是吡啶类农药开发最成功的产品之一 ,但其中间体 2 氯 5 氯甲基吡啶的合成工艺较复杂。用 2 溴 5 噻吩基 甲基取代吡虫啉分子中的氯吡啶甲基 ,合成了 1 ( 2 溴 5 噻吩基 ) 甲基 2 硝基亚氨基咪唑烷 ,产率 54%。以萝卜蚜为测试虫进行的杀虫效果实验显示 ,LD50 ( 2 4h)为 6 3mg kg ,是一种合格的农药先导化合物 ,具有进行结构优化形成优秀农药的良好前景。
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| 关 键 词： | 吡虫啉 1-(2-溴-5-噻吩基)甲基-2-硝基亚氨基咪唑烷 农药先导化合物 杀虫实验 |
Synthesis and Insecticidal Tests of Imidacloprid Related Compounds |
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| MO Xian-zhong,CHEN Wen-na,PAN Ying-ming,ZHANG Qiao-ping,CUI Jian-guo,WEN Xiao-ling.Synthesis and Insecticidal Tests of Imidacloprid Related Compounds[J].Fine Chemicals,2000,17(8):447-449. |
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| Authors: | MO Xian-zhong CHEN Wen-na PAN Ying-ming ZHANG Qiao-ping CUI Jian-guo WEN Xiao-ling |
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| Abstract: | Five analogs of imidacloprid,1 (2 chloro 5 pyridyl) methyl 2 nitroiminoimidazolidine,were synthesized by replacing the pyridyl group of imidacloprid with other heterocyclic groups.The insecticidal tests of the five compounds on lipaphis erysimi were also carried out.Thus,replacement of the 2 chloropyridyl group of imidacloprid with 2 bromo 5 thienyl group resulted in 1 (2 bromo 5 thienyl) methyl 2 nitroiminoimidazolidine in 54% yield.In the insecticidal tests,it was found that the LD 50 (24 h) of lipaphis erysimi was 6 3 mg/kg.The synthesized compounds are eligible for pesticide's leadercompounds and show prospective value for their further structural optimization. |
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| Keywords: | imidacloprid 1 (2 bromo 5 thienyl) methyl 2 nitroiminoimidazolidine pesticide's leadercompounds insecticidal tests |
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