Nonenzymatic hydrolysis of phosphatidylcholine prepared as liposomes and mixed micelles |
| |
| Authors: | Rodney J. Y. Ho Mark Schmetz David W. Deamer |
| |
| Affiliation: | (1) Department of Zoology, University of California, 95616 Davis, CA;(2) Department of Biochemistry, University of Tennessee, 37996-0840 Knoxville, TN |
| |
| Abstract: | Nonenzymatic hydrolysis of phosphatidylcholine was investigated at several pH ranges in liposomes and mixed micelles. Phosphatidylcholine was stable to hydrolysis for 140 hr at pH 4, 7 and 10, but slowly hydrolyzed at pH 1 with a half-time of 50 hr. We conclude that phosphatidylcholine is not significantly degraded by hydrolysis under conditions typical for liposome preparation methods. |
| |
| Keywords: | |
| 本文献已被 SpringerLink 等数据库收录！ |
|
