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Protecting biodegradable coatings releasing antimicrobial agents
Authors:Fabienne Fay  Isabelle Linossier  Valérie Langlois  Karine Vallee‐Rehel  Michal Y. Krasko  Abraham J. Domb
Affiliation:1. Laboratoire de Biotechnologie et Chimie Marines, EA 3884, Université de Bretagne‐Sud, BP 92116, 56321 Lorient Cedex, France;2. Laboratoire de Recherche sur les Polymères, Unités Mixtes De Recherche, Centre National de la Recherche Scientifique 7581, 2‐8 Rue H Dunant 94320 Thiais, France;3. Department of Medicinal Chemistry and Natural Products, School of Pharmacy, Faculty of Medicine, Hebrew University of Jerusalem, 91120 Jerusalem, Israel;4. A. J. Domb is affiliated with the Devid R. Bloom Center for Pharmacy and the Alex Grass Center for Synthesis and Drug Design at the Hebrew University of Jerusalem.
Abstract:This article describes the synthesis and in vitro analysis of poly(ester anhydride) antimicrobial protection coatings. Poly(ester anhydride)s composed of ricinoleic acid, sebacic acid, terephthalic acid, and isophthalic acid were used in this study. The polymers were compatible with various fillers commonly used in paint preparation. The in vitro experiments showed that the polymers are able to release diuron, an antimicrobial agent, for months. © 2007 Wiley Periodicals, Inc. J Appl Polym Sci 2007
Keywords:biodegradable  coatings  dyes/pigments  films  polyaromatics
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