| 癫痫发作的两种模式 |
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| 引用本文： | 赖永秀,夏阳,万衡,雷町,尧德中. 癫痫发作的两种模式[J]. 电子科技大学学报(自然科学版), 2010, 39(3): 454-456. DOI: 10.3969/j.issn.1001-0548.2010.03.029 |
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| 作者姓名： | 赖永秀 夏阳 万衡 雷町 尧德中 |
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| 作者单位： | 1.电子科技大学神经信息教育部重点实验室 成都 610054; |
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| 基金项目： | 国家自然科学基金，四川省科技厅项目 |
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| 摘 要： | 通过分析临床癫痫脑电的最大Lyapunov指数，研究了多种不同诱发背景的癫痫在各个时期(间期、前期、发作期、发作后期4个时段)的最大Lyapunov指数的时域变化规律，提出癫痫发作具有两种响应模式:(1)睡眠、清醒等状态下的自发癫痫，大脑受到随机信号的干扰，脑内各子系统之间需经过较复杂的协调作用才能进入高度同步放电状态；(2)闪光刺激等状态下的诱发癫痫，大脑受到外加高频信号的干扰，脑内各子系统将被快速驱动进入高度同步放电状态。
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| 关 键 词： | 癫痫脑电 发作期 最大Lyapunov指数 发作间期 癫痫发作 |
| 收稿时间： | 2009-06-10 |
Two Models of Epileptic Seizure |
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| LAI Yong-xiu,XIA Yang,WAN Heng,LEI Ding,YAO De-zhong. Two Models of Epileptic Seizure[J]. Journal of University of Electronic Science and Technology of China, 2010, 39(3): 454-456. DOI: 10.3969/j.issn.1001-0548.2010.03.029 |
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| Authors: | LAI Yong-xiu XIA Yang WAN Heng LEI Ding YAO De-zhong |
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| Affiliation: | 1.Key Laboratory for NeuroInformation of Ministry of Education,University of Electronic Science and Technology of China Chengdu 610054;2.WestChina Hospital,Sichuan University Chengdu 610041 |
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| Abstract: | Based on the clinical epileptic electroencephalography (EEG) data, the time courses of the largest Lyapunov exponent (LLX) are investigated for different states (i.e. interictal, preictal, ictal and postictal) of seizures induced from different background. Two seizure response models are proposed. (1) for seizures occurring in sleep or wake state, it seems that the brain is disturbed by a random signal, so that the subsystems of the brain will need a complex interaction to get into a highly synchronous rhythm. (2) for seizures induced by flash stimulation, it likes that the brain is interfered by a strongly high frequency signal, so that the subsystems of the brain will be driven directly into a similar oscillation. |
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