Deficient repair of UV-induced DNA damage in immature human T cells |
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Authors: | M Hartwig |
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Affiliation: | Max Delbrück Center for Molecular Medicine, Berlin. |
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Abstract: | As compared with quiescent lymphocytes, human thymocytes were found in the nucleoid sedimentation assay to be deficient in UV-induced DNA repair. Therefore, the age-related repair deficiency of human lymphocytes can result from the increased proportion of immature T cells occurring with age. |
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