Enhancing microcantilever capability with integrated AC electroosmotic trapping |
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Authors: | N Islam M Lian J Wu |
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Affiliation: | (1) Department of Electrical and Computer Engineering, The University of Tennessee, Knoxville, TN 37996, USA |
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Abstract: | Microcantilevers are finding wide applications in detecting biochemical agents. However, their usage has been limited to highly
concentrated samples to ensure sufficient deposition of agents onto cantilevers. A pre-concentration or enrichment step will
expand their application range to more dilute, practical samples and real-time detection. This paper reports the integration
of in-situ particle concentrators on microcantilevers. Only a thin metal layer on microcantilevers is required to generate
microfluidic convection of particles from solution bulk onto microcantilever surfaces, greatly enriching local particle counts
and enhancing sensitivity of the system. A working prototype is presented in the paper. Preliminary experiments concentrating
latex particles were conducted and the particle concentration effect has been experimentally verified using AFM probes as
microcantilevers. As ACEO concentrator has no dependence on particle properties, the method is expected to be applicable to
bio-particles collection. |
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Keywords: | AC electroosmosis Microfluidic Particle trapping Microcantilever |
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