| RP-HPLC测定盐酸安非他酮中间氯苯甲酸杂质的含量 |
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| 引用本文： | 厉凤英,朱鹏,史向红,余珍艳,王鸿. RP-HPLC测定盐酸安非他酮中间氯苯甲酸杂质的含量[J]. 化学工程师, 2010, 24(11): 27-28,30 |
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| 作者姓名： | 厉凤英 朱鹏 史向红 余珍艳 王鸿 |
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| 作者单位： | [1]浙江普洛家园药业有限公司,浙江东阳322118 [2]浙江工业大学药学院。浙江杭州310014,浙江东阳322118 |
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| 摘 要： | 建立了一个测定抗抑郁药盐酸安非他酮中间氯苯甲酸杂质的高效液相色谱方法,该方法准确、灵敏、精密度高,可用于抗抑郁药盐酸安非他酮中间氯苯甲酸杂质的含量测定。
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| 关 键 词： | 反相高效液相色谱法 盐酸安非他酮 间氯苯甲酸 含量测定 |
Determination of m-chlorobenzoic acid in bupropion hydrochloride by RP-HPLC |
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| LI Feng-ying,ZHU Peng,SHI Xiang-hong,YU Zhen-yan,WANG Hong. Determination of m-chlorobenzoic acid in bupropion hydrochloride by RP-HPLC[J]. Chemical Engineer, 2010, 24(11): 27-28,30 |
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| Authors: | LI Feng-ying ZHU Peng SHI Xiang-hong YU Zhen-yan WANG Hong |
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| Affiliation: | 1.Apela Jiayuan Pharmaceutical Co.,Doyang 322118,China;2.College of Pharmaly,Zhejiang University of Techology,Hangzhou 310014,China) |
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| Abstract: | A RP-HPLC method for the determination of m-chlorobenzoic acid in the antidepressant of bupropion hydrochloride was estab lised.The method was proved to be accurate,sensitive and precise.It can be applied for the content assay of m-chlorobenzoic acid in the bupropion hydrochloride. |
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| Keywords: | RP-HPLC bupropion hydrochloride m-chlorobenzoic acid assay |
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