Synthesis and functionalization of nanoengineered materials using click chemistry |
| |
| Authors: | Georgina K. SuchAngus P.R. Johnston Kang LiangFrank Caruso |
| |
| Affiliation: | Department of Chemical and Biomolecular Engineering, The University of Melbourne, Parkville, Victoria 3010, Australia |
| |
| Abstract: | The synthesis of nanoengineered materials with precise control over material composition, architecture and functionality is integral to advances in diverse fields, including biomedicine. Over the last 10 years, click chemistry has emerged as a prominent and versatile approach to engineer materials with specific properties. Herein, we highlight the application of click chemistry for the synthesis of nanoengineered materials, ranging from ultrathin films to delivery systems such as polymersomes, dendrimers and capsules. In addition, we discuss the use of click chemistry for functionalizing such materials, focusing on modifications aimed at biomedical applications. |
| |
| Keywords: | Ab, antibody ATRP, atom transfer radical polymerization Az, azide BSA, bovine serum albumin Cu, copper CuAAC, copper-catalyzed alkyne-azide cycloaddition CB(6), cucurbit[6]uril CD, cyclodextrin DA, Diels-Alder [4+2] cycloaddition DNA, deoxyribose nucleic acid DOX, doxorubicin EDC, 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide ene alkene HYA, hyaluronan LbL, layer-be-layer assembly LCST, lower critical solution temperature NAS, N-acroyloxysuccinimide NCCM, noncovalently connected micelle NHS, N-hydroxy succinimide PAA, poly(acrylic acid) PBLG, poly(γ-benzyl- smallcaps" >l-glutamate) PCL, poly(?-caprolactone) PDPA, poly(2-diisopropylamino ethyl methacrylate) PEG, poly(ethylene glycol) PHEMA, poly(2-hydroxy ethyl methacrylate) PGAAlk, alkyne-modified poly( smallcaps" >l-glutamic acid) PGA, poly( smallcaps" >l-glutamic acid) PMA, poly(methacrylic acid) PMMA, poly(methyl methacrylate) PNIPAM, poly(N-isopropylacrylamide) POEGMA-PDMA-PDEA, poly(oligo(ethylene glycol) monomethyl ether methacrylate)-b-poly(2-dimethylamino) ethyl methacylate-b-poly(2-diethylamino) ethyl methacylate) PPDSM, poly(pyridyl disulfide ethyl methacrylate) PS, poly(styrene) PSS, poly(styrene sulfonate) PtBA, poly(tert-butyl acrylate) PVPON, poly(N-vinyl pyrrolidone) Qβ, capsid of bacteriophage rDA, retro-Diels-Alder RGD, arginine-glycine-aspartic acid ROP, ring opening polymerization SAMs, self-assembled monolayers SPAAC, strain-promoted cycloaddition of alkynes and azide SPIO, superparamagnetic iron oxide |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
