Porous polymer particles—A comprehensive guide to synthesis, characterization, functionalization and applications |
| |
| Authors: | M. Talha GokmenFilip E. Du Prez |
| |
| Affiliation: | Polymer Chemistry Research Group, Department of Organic Chemistry, Ghent University, Krijgslaan 281 S4 9000 Gent, Belgium |
| |
| Abstract: | This review is written to fulfill the need of a comprehensive guide for the manufacture of porous polymer particles. The synthesis section discusses and for the first time compares microfluidics, membrane/microchannel, suspension, dispersion, precipitation, multistage polymerizations and a few other less known methods, microfluidics being in greater detail. The comparison includes on one hand simplicity, scaling-up possibilities and the ability to yield nonspherical particles for these methods and on the other hand size, size monodispersity, pore characteristics and chemical functionality of the obtained particles. This extensive comparison certainly makes this review also useful for the preparation of nonporous particles. In addition, functionalization/characterization techniques and applications of porous particles are also discussed, including some visionary recommendations. The review is expected not only to enable individual experts of each field to compare their methods with the other ones, but also to be a handbook for the newcomers to this field to guide them from the synthesis to the applications. |
| |
| Keywords: | AIBN, 2,2&prime -azobis(2-methylpropionitrile) ASTM, American Society for Testing and Materials CuAAC, Cu(I) catalyzed azide-alkyne cycloaddition CV, coefficient of variation defined as (σ/Dp) × 100 where Dp is the number average diameter and σ is the standard deviation on the diameter DSC, differential scanning calorimetry DVB, divinylbenzene EGDMA, ethylene glycol dimethacrylate EtOH, ethanol Fmoc, fluorenylmethyloxycarbonyl GMA, glycidyl methacrylate HEMA, 2-hydroxyethyl methacrylate HIPE, high internal phase emulsion HPLC, high performance liquid chromatography MeOH, methanol MMA, methyl methacrylate MW, molecular weight O/W, oil-in-water emulsion PDMS, poly(dimethylsiloxane) PEO, poly(ethylene oxide) PMMA, poly(methyl methacrylate) PS, polystyrene PVA, poly(vinylalcohol) SDS, sodium dodecyl sulfate SEC, size exclusion chromatography SEM, scanning electron microscopy SPOS, solid phase organic synthesis SPPS, solid phase peptide synthesis SPG, Shirazu porous glass TEM, transmission electron microscope TGA, thermogravimetric analysis THF, tetrahydrofuran UV, ultraviolet W/O, water-in-oil emulsion |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
