| 5-溴香兰素的绿色合成 |
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| 引用本文： | 彭安顺,英荣建.5-溴香兰素的绿色合成[J].化学工程师,2009,23(7):67-68. |
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| 作者姓名： | 彭安顺 英荣建 |
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| 作者单位： | 临沂师范学院,化学系,山东,临沂,276005 |
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| 摘 要： | 以冰醋酸为溶剂,香兰素为原料,AlBr3为催化剂,HBrO3与KBrO3为溴化剂合成了5-溴香兰素.采用正交实验法考察了影响收率的因素.最佳条件为:香兰素、KBrO3与AlBr3的物质的量的摩尔比为1:0.5:0.056,反应时间6.0h,反应温度30℃.在优化条件下收率可达90.4%.产物结构通过IR、1HNMR、熔点测定和元素分析得以确认.
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| 关 键 词： | 香兰素 溴化反应 合成 5-溴香兰素 |
Green synthesis of 5-bromo-vanillin |
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| PENG An-shun,YING Rong-jian.Green synthesis of 5-bromo-vanillin[J].Chemical Engineer,2009,23(7):67-68. |
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| Authors: | PENG An-shun YING Rong-jian |
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| Affiliation: | Department of Chemistry;Linyi Normal University;Linyi 276005;China |
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| Abstract: | 5-bromo-vanillin was synthesizedby using vanillin as raw material,aluminium chloride as catalyst, hydrobromic acid and potassium bromate as brominating agent and acetic acid as solvent.Factors influencing the yield were investigated by the orthogonal experimental method.The optimum conditions are as follows:Vanillin: potassium bromate:aluminium chloride is 1mol:0.5mol:0.056mol, reaction time is 6.0h,reaction temperature is 30%. The yield is above 90.4% under the optimum conditions. The title compound was characterized by IR,1H NMR,mp. Measurement and element analysis. |
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| Keywords: | vanillin bromination synthesis 5-bromo-vanillin |
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