我国居民膳食中甜蜜素暴露的理论风险评估

目的评估我国居民膳食中甜蜜素暴露水平及对我国居民健康状况的潜在风险。方法根据GB 2760—2014《食品添加剂使用标准》中规定允许使用甜蜜素的各类食品中甜蜜素的最大使用量和我国居民各类食品实际的消费量数据,采用简单分布模型方法,对我国居民全人群通过各类食品摄入甜蜜素的摄入量进行理论估计,并与国际组织制定的甜蜜素每日允许摄入量(ADI)进行比较。结果我国居民全人群每日通过各类食品摄入甜蜜素的平均水平为0.97 mg/kg BW,占ADI值的13.86%。高暴露人群(P97.5)每日通过各类食品摄入甜蜜素的量为6.69 mg/kg BW,占ADI值的95.52%。根据欧盟食品科学委员会(SCF)制订的ADI(7.00 mg/kg BW),各年龄组人群通过相应食品摄入甜蜜素的平均摄入量均未超过ADI值,但是2~3岁、4~9岁、10~17岁人群中的高暴露人群(P97.5)其甜蜜素的摄入量分别超过甜蜜素ADI的146.32%、86.78%、9.19%;糕点、带壳熟制坚果与籽类对我国居民膳食中甜蜜素暴露的贡献率较高。结论我国居民全人群通过GB 2760—2014中规定允许使用甜蜜素的各类食品摄入甜蜜素的水平均处于安全水平,但是我国部分高暴露人群的暴露水平应引起关注。

Theoretical risk assessment for dietary exposure to sodium cyclamate in Chinese population

In order to assess the potential risk of dietary exposure to sodium cyclamate in Chinese population.Methods The limits of sodium cyclamate in foods and consumption of these foods were used for exposure assessment. The exposure of sodium cyclamate obtained in the present research was compared with the acceptable daily intake (ADI) which was established by JECFA.Results The average exposure of sodium cyclamate exposure of whole Chinese population was 0.97 mg/kg BW, accounted for 13.86% of ADI, while high exposure (P97.5) was 6.69 mg/kg BW and accounted for 95.52% of ADI. According to SCF, the intake of sodium cyclamate exposure of high exposures in people under 2-3 years, 4-9 years, 10-17 years (P97.5) exceeded ADI, was 146.32%,86.78%,9.19%, respectively. Pastry, shell cooked nuts and seeds, were the main sources of sodium cyclamate exposure compared with others.Conclusion The sodium cyclamate dietary exposure of whole Chinese population was below the ADI. The sodium cyclamate exposure in high exposures (P97.5) should be paid more attention to.