| 氯吡格雷临床研究出血事件综述 |
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| 引用本文： | 袁真,陈碧莲. 氯吡格雷临床研究出血事件综述[J]. 金属学报, 2021, 26(3): 341-349. DOI: 10.12092/j.issn.1009-2501.2021.03.015 |
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| 作者姓名： | 袁真 陈碧莲 |
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| 作者单位： | 中南大学湘雅医院老年病科,长沙 410008,湖南 |
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| 基金项目： | 湖南省科技厅自然科学基金项目（2018JJ2653）;湖南省卫生厅科研项目（20201525） |
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| 摘 要： | P2Y12受体拮抗剂是目前治疗急性冠状动脉综合征常用药物之一,氯吡格雷是P2Y12受体拮抗剂中的代表药物,出血事件作为该药最常见的副作用也一直受到关注。本文对氯吡格雷大型临床研究中出血事件的发生率及风险进行分析和探讨,为临床上合理处方氯吡格雷提供参考。
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| 关 键 词： | 氯吡格雷 出血事件 出血标准 |
| 收稿时间： | 2020-12-21 |
| 修稿时间： | 2021-02-06 |
Review of bleeding events in clinical studies of clopidogrel |
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| YUAN Zhen,CHEN Bilian. Review of bleeding events in clinical studies of clopidogrel[J]. Acta Metallurgica Sinica, 2021, 26(3): 341-349. DOI: 10.12092/j.issn.1009-2501.2021.03.015 |
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| Authors: | YUAN Zhen CHEN Bilian |
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| Affiliation: | Department of Geriatrics, Xiangya Hospital, Central South University, Changsha 410078, Hunan, China |
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| Abstract: | P2Y12 receptor antagonist is currently one of the commonly used drugs for the treatment of acute coronary syndromes. Clopidogrel is a representative drug among P2Y12 receptor antagonists. Bleeding events as the most common side effect of this drug have also been concerned. The incidence and risk of bleeding events in large-scale clinical studies of clopidogrel are analyzed and discussed to provide refer-ences for reasonable clinical prescription of clopidogrel. |
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| Keywords: | clopidogrel bleeding events bleeding definition |
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