抗菌剂对聚乙烯表面生物被膜的抑制

采用共混方法在低密度聚乙烯中分别加入银系抗菌剂和Triclosan制备出两种改性聚乙烯,研究了材料的抗菌性能和抗菌剂对试样表面生物被膜的抑制作用.结果表明,两种改性聚乙烯对大肠杆菌和金黄色葡萄球菌都有良好的抗菌效果;细菌生物被膜的形成主要包括粘附、繁殖和成熟3个阶段,添加Triclosan的试样可以在生物被膜成熟前显著杀灭样品表面的细菌,阻止细菌在其表面粘附和繁殖,从而抑制生物被膜形成.空白试样和银系抗菌剂改性试样表面均有大量细菌粘附并形成生物被膜.

Inhibitory effect of antimicrobial agent on biofilm formation on polyethylene surface

Triclosan and silver antibacterial agent were incorporated into polyethylene by blending. The antimicrobial efficacy of modified samples and inhibitory effect of antimicrobial agent on biofilm formation on the LDPE surface were investigated. The results showed that both of modified LDPE samples exhibited excellent antimicrobial performance against S. aureus and E. coli. The formation of  biofilm could be described as a three–stage process: adhesion, proliferation and biofilm maturation. The adhesion and propagation of bacteria were evidently reduced by triclosan added into LDPE, thereby the formation of biofilm was prevented. However, the amount of bacteria on the surface of LDPE adding silver antimicrobial agent was no less than that on the control sample. Silver antimicrobial agent could not make much difference in biofilm formation on surfaces.