| 3-甲基-1-(2-(1-哌啶基)苯基)丁基胺的合成 |
| |
| 引用本文： | 侯瑞珍,李秋先. 3-甲基-1-(2-(1-哌啶基)苯基)丁基胺的合成[J]. 吉林化工学院学报, 2003, 20(4): 30-31 |
| |
| 作者姓名： | 侯瑞珍 李秋先 |
| |
| 作者单位： | 长春工业大学,化学工程学院,吉林,长春,130012 |
| |
| 摘 要： | 以3-甲基-1(2-哌啶基苯基)丁基酮为原料,采用Leuckart反应合成3-甲基-1.(2-(1-哌啶基)苯基) 丁基胺,最终化合物经核磁共振氢谱及碳谱得到确证.
|
| 关 键 词： | 3-甲基-1-(2-(1-哌啶基)苯基)丁基胺 Leuckart反应 合成 |
| 文章编号： | 1007-2853(2003)04-0030-02 |
| 修稿时间： | 2003-09-04 |
Synthesis of 3-methyl-1-(2-(1-piperidiny) phenyl)-butylamine |
| |
| HOU Rui-zhen,LI Qiu-xian. Synthesis of 3-methyl-1-(2-(1-piperidiny) phenyl)-butylamine[J]. Journal of Jilin Institute of Chemical Technology, 2003, 20(4): 30-31 |
| |
| Authors: | HOU Rui-zhen LI Qiu-xian |
| |
| Abstract: | The 3-methyl-1-(2-(1-piperidiny) phenyl)-butylamine is the key intermediate of Repaglinide. It was synthesized from 3-methyl-1-(2-piperidiny) phenyl)-butylketone through Leuckart reaction. Because the route did not require high pressure, the process was simple and safety. The total yield was 30% . The structures of the intermediate and the target molecule were confirmed by 1H NMR and 13CNMR spectrum. |
| |
| Keywords: | 3-methyl-1-(2-(1-piperidiny) phenyl)-butylamine Leuckart reaction synthesis |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
