| 茅台酱香型酒糟和酒曲脂溶性成分及抗菌活性研究 |
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| 引用本文： | 王兴东,牟明月,康文艺,张前军,周清娣,卫 钢. 茅台酱香型酒糟和酒曲脂溶性成分及抗菌活性研究[J]. 中国酿造, 2016, 35(12): 44. DOI: 10.11882/j.issn.0254-5071.2016.12.009 |
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| 作者姓名： | 王兴东 牟明月 康文艺 张前军 周清娣 卫 钢 |
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| 作者单位： | 1.贵州大学 化学与化工学院，贵州 贵阳 550025；2.贵州茅台酒股份有限公司，贵州 仁怀 564501；3.河南大学 药学院，河南 开封 475004；4.悉尼大学 化学院，悉尼 新南威尔士州 2006；5.澳大利亚联邦科学与工业研究组织，悉尼 新南威尔士州 2070 |
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| 基金项目： | 教育部春晖计划项目(Z2015003) |
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| 摘 要： | 采用气相色谱-质谱（GC-MS）技术对茅台酱香型酒糟与酒曲石油醚萃取部分的脂溶性成分进行分析，通过K-B纸片法评价茅台酱香型酒糟与酒曲脂溶性成分的体外抑菌活性。结果表明，从茅台酱香型酒糟与酒曲的脂溶性成分中分别鉴定出18种化合物，占总峰面积的100%。其中烷烃类（50.19%）、酯类（49.58%）为茅台镇酒糟主要脂溶性成分类型，茅台镇酒曲脂溶性成分主要为烷烃类化合物（95.79%）。抑菌实验表明，茅台酱香型酒曲石油醚提取物对金黄色葡萄球菌（SA）、耐甲氧西林金黄色葡萄球菌（MRSA）和产超广谱β-内酰胺酶的金黄色葡萄球菌（ESBLs-SA）均有抑制作用，其中对MRSA抑制作用最好，抑菌圈直径为8 mm。
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| 关 键 词： | 酱香型酒糟 酱香型酒曲 脂溶性成分 气相色谱-质谱法 抑菌活性 |
Antibacterial activities analysis of the liposoluble components from Moutai distiller's grains and Jiuqu |
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| WANG Xingdong,MU Mingyue,KANG Wenyi,ZHANG Qianjun,ZHOU Qingdi,WEI Gang. Antibacterial activities analysis of the liposoluble components from Moutai distiller's grains and Jiuqu[J]. China Brewing, 2016, 35(12): 44. DOI: 10.11882/j.issn.0254-5071.2016.12.009 |
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| Authors: | WANG Xingdong MU Mingyue KANG Wenyi ZHANG Qianjun ZHOU Qingdi WEI Gang |
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| Affiliation: | 1.College of Chemistry and Engineering, Guizhou University, Guiyang 550025, China; 2.Kweichow Moutai Co., Ltd., Renhuai 564500, China; 3.Pharmaceutical College of Henan University, Kaifeng 475004, China; 4.College of Chemistry, The University of Sydney,
New South Wales 2006, Australia; 5.CSIRO Manufacturing, 218, New South Wales 2070, Australia) |
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| Abstract: | Liposoluble components from Moutai distiller's grains and Jiuqu with petroleum ether extraction of were analyzed by GC-MS. The in vitro antibacterial activity was determined by K-B method. The results showed that 18 compounds were identified respectively from Moutai distiller's grains and Jiuqu, accounting for 100% of the total detected constituents. Alkanes (50.19%) and esters (49.58%) were the main compound types in Moutai distiller's grains; and alkanes (95.79%) were the main compound type in Jiuqu. The extract from Jiuqu with petroleum ether extraction had a significant antibacterial effect on Staphylococcus aureus, methcillin-resistant S. aureus (MRSA) and extended spectrum β-lactamase S. aureus (ESBLs-SA), the effect on MRSA was the most significant, and the inhibition zone was 8 mm. |
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| Keywords: | Moutai distiller's grains Moutai-flavor Jiuqu liposoluble components GC-MS antimicrobial activity |
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