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Synthesizing within-host and population-level selective pressures on viral populations: the impact of adaptive immunity on viral immune escape |
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| Authors: | Igor Volkov Kim M Pepin James O Lloyd-Smith Jayanth R Banavar Bryan T Grenfell |
| Affiliation: | 1.Department of Physics, The Pennsylvania State University, University Park, PA 16802, USA;2.Department of Biology, The Pennsylvania State University, University Park, PA 16802, USA;3.Department of Ecology and Evolutionary Biology, UCLA, Los Angeles, CA 90095, USA;4.Department of Ecology and Evolutionary Biology and Woodrow Wilson School, Princeton University, Princeton, NJ 08544, USA;5.Fogarty International Center, National Institutes of Health, Bethesda, MD 20892, USA |
| Abstract: | |
| Keywords: | immune escape within-host evolution viral evolution adaptive immune response cross-scale dynamics viral quasi-species |