| 改性介孔分子筛对布洛芬的吸附与控制释放 |
| |
| 引用本文： | 陈雷,张翻,邵新超,梁俊虎,宋丽娟.改性介孔分子筛对布洛芬的吸附与控制释放[J].化学工业与工程,2011,28(4):11-15. |
| |
| 作者姓名： | 陈雷 张翻 邵新超 梁俊虎 宋丽娟 |
| |
| 作者单位： | 辽宁石油化工大学 辽宁省石油化工重点实验室,辽宁抚顺,113001 |
| |
| 基金项目： | 国家自然基金资助项目(20976007) |
| |
| 摘 要： | 采用合成后改性将氨基嫁接进介孔MCM41和SBA-15孔道内，对功能化的2种分子筛进行药物吸附与控制释放的研究。利用红外光谱仪(IR)、智能重量分析仪(IGA)等表征手段对吸附剂的物理结构和化学组成进行表征。对药物布洛芬(IBU)的吸附量进行比较，结果表明，氨基改性的MCM41(MCM41-NH2)对布洛芬的吸附性能大...
|
| 关 键 词： | MCM41-NH2 SBA-15-NH2 布洛芬 吸附 缓释 |
Amine-Functionalized Mesoporous Materials as Carriers for Adsorption and Controlled Drug Delivery of Ibuprofen |
| |
| CHEN Lei,ZHANG Fan,SHAO Xin-chao,LIANG Jun-hu,SONG Li-juan.Amine-Functionalized Mesoporous Materials as Carriers for Adsorption and Controlled Drug Delivery of Ibuprofen[J].Chemical Industry and Engineering,2011,28(4):11-15. |
| |
| Authors: | CHEN Lei ZHANG Fan SHAO Xin-chao LIANG Jun-hu SONG Li-juan |
| |
| Affiliation: | CHEN Lei,ZHANG Fan,SHAO Xin-chao,LIANG Jun-hu,SONG Li-juan(Liaoning Shihua University,Liaoning Key Laboratory of Petrochemical Engineering,Fushun 113001,China) |
| |
| Abstract: | Mesoporous materials were modified with amine groups after synthesis,the functionalized MCM-41 and SBA-15 were investigated as matrix for adsorption and controlled drug delivery.The structure,composition and framework of the matrix were characterized by infrared spectrometer(IR) and intelligent gravitation analyzer(IGA).MCM-41-NH2 showed higher loading capacity of IBU than SBA-15-NH2.Releasing experiments showed,IBU released more slowly from two medium at pH=2.0,and released more slowly from S-NH2-IBU than ... |
| |
| Keywords: | MCM-41-NH2 SBA-15-NH2 ibuprofen adsorption drug delivery |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
