| 苯并咪唑衍生物的微波合成、表征及其抑菌活性 |
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| 引用本文： | 刘波,吕维忠,吴奕光,倪卓,高原,刘剑洪. 苯并咪唑衍生物的微波合成、表征及其抑菌活性[J]. 广州化工, 2006, 34(6): 18-20 |
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| 作者姓名： | 刘波 吕维忠 吴奕光 倪卓 高原 刘剑洪 |
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| 作者单位： | 深圳大学化学与化工学院,广东,深圳,518060;深圳大学化学与化工学院,广东,深圳,518060;深圳大学化学与化工学院,广东,深圳,518060;深圳大学化学与化工学院,广东,深圳,518060;深圳大学化学与化工学院,广东,深圳,518060;深圳大学化学与化工学院,广东,深圳,518060 |
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| 摘 要： | 在微波辐射下分别用对甲氧基苯甲醛、对羟基苯甲醛和邻苯二胺反应直接关环合成了1-(对甲氧基苄基)-2-(对甲氧基苯基)-苯并咪唑、1-(对羟基苄基)-2-(对羟基苯基)-苯并咪唑化合物.通过数字熔点仪、元素分析、红外光谱分析、核磁分析对产品进行了表征,并对这两种苯并咪唑衍生物的抑菌活性进行了研究。
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| 关 键 词： | 苯并咪唑 微波辐射 合成 表征 抑菌活性 |
Microwave Synthesis, Characteristics and Antibacterial Activities of Benzimidazole Derivatives |
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| LIU Bo,LV Wei-zhong,WU Yi-guang,NI Zhuo,GAO Yuan,LIU Jian-hong. Microwave Synthesis, Characteristics and Antibacterial Activities of Benzimidazole Derivatives[J]. GuangZhou Chemical Industry and Technology, 2006, 34(6): 18-20 |
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| Authors: | LIU Bo LV Wei-zhong WU Yi-guang NI Zhuo GAO Yuan LIU Jian-hong |
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| Affiliation: | College of Chemistry and Chemical Engineering,Shenzhen University, Shenzhen 518060, China |
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| Abstract: | 1-(p-Methoxybenzyl)-2-(p-thoxyphenyl)-benzimidazole and 1-(p-hydroxybenzyl)-2-(p-hydroxyphenyl)-benzimidazole were snythesized by the condensation of o-phenylenediamine with p-methoxybenzaldehyde and p-hydroxyheozaldehyde under microwave irradiation,and characterized by melting point determination,elements analysis,IR and 1HNMR spectra.Antibacterial activities of the two benzimidazole derivatives were studied. |
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| Keywords: | benzimidazole microwave irradiation synthesis characteristics antibacterial activities |
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