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Optimizing the concentration of quaternary ammonium dimethacrylate monomer in bis-GMA/TEGDMA dental resin system for antibacterial activity and mechanical properties
Authors:Xiaoxu Liang  Eva Söderling  Fang Liu  Jingwei He  Lippo V J Lassila  Pekka K Vallittu
Affiliation:1. College of Materials Science and Engineering, South China University of Technology, Guangzhou, 510641, China
2. Institute of Dentistry, University of Turku, 20520, Turku, Finland
3. Department of Biomaterials Science, Institute of Dentistry and Biocity Turku Biomaterials Research Program, University of Turku, 20520, Turku, Finland
4. Turku Clinical Biomaterials Center (TCBC), University of Turku, 20520, Turku, Finland
Abstract:Four novel quaternary ammonium dimethacrylate monomers named IMQ (side alkyl chain length from 12 to 18) were synthesized with the aim to synthesize dental resin with antibacterial activity. All of IMQs were added into bis-GMA/TEGDMA dental resin system with a series of mass ratio (5, 10, and 20 wt%), double bond conversion (DC), flexural strength (FS), modulus of elasticity (FM) and biofilm formation inhibitory effect were studied. According to the results of DC, FS, FM, and the biofilm inhibitory effect, IMQ-16 containing polymer had the best comprehensive properties, and the optimal concentration of IMQ-16 in bis-GMA/TEGDMA dental resin would be in the range of 5–10 wt%.
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