Affiliation: | Laboratoire de Sciences Animales, ENSAIA-INPL-INRA, BP 172, 54505, Vandoeuvre-lès-Nancy, France |
Abstract: | The aim of this work was to characterize phenanthrene, pyrene, benzo(a)pyrene and TCDD transfer to milk, urine and faeces in lactating goats after a single oral ingestion (2.5 106 Bq) of 14C]phenanthrene, 14C]pyrene, 14C]benzoa]pyrene or 14C]2,3,7,8-TCDD. Seven hours after 14C] PAHs oral ingestion, a radioactivity peak was detected in plasma for all compounds studied. Regarding excretion routes, three specific types of behaviour were noticed: 2,3,7,8-TCDD was mainly excreted in milk (7.8%) and a large part of radioactivity ingested remained in the organism (71.2%). Phenanthrene and pyrene presented a similar behaviour, with a low milk transfer (1.6% and 1.9%, respectively) and a high excretion through urine (40.4% and 11.4%, respectively) suggesting their metabolization. Benzoa]pyrene was poorly absorbed (88% of the ingested part of this compound was detected in faeces) and radioactivity due to benzoa]pyrene was not significantly detected in milk (0.2%). |