聚氨酯/碳纳米纤维复合材料的结构和抗凝血性能

分别采用溶液共混和熔融共混的方法制备出聚氯酯／碳纳米纤维复合材料，研究了碳纳米纤维对聚氯酯的热行为和表面微观化学组成的影响，并观察和测定了血小板在复合材料表面的粘附以及血液中血红蛋白浓度、纤维蛋白原浓度的变化，分析了碳纳米纤维对聚氯酯血液相容性的影响．结果表明，引入碳纳米纤维后，聚氯酯复合材料的表面氧含量有不同程度的提高，玻璃化转变温度及熔融温度都发生了改变；血小板在复合材料表面的粘附受到明显的抑制；经血泵循环4h后，在与聚氯酯复合材料表面接触的血液中，血红蛋白和纤维蛋白原浓度的变化相对减小；复合材料的血液相容性提高．

Structure and hemocompatibility of polymer/carbon nanofiber composite

To investigate the effects of carbon nanofiber as a dispersed phase on the blood compatibility of polyurethanes matrix, a nanostuctured organic/inorganic composite film was prepared by dispersing carbon nanofiber into polyurethanes. The changes of either the surface chemistry composition (O/N) and the glass transition temperature and the melting temperature were observed through the analysis data of ESCA and DSC respectively. The hemocompatibilities of the composites were tested through platelet adhesion measurement by using epifluorescent video microscopy and the variation of fibrinogen and free haemoglobin concentration in the blood contacting the composite respectively. It was shown that the platelet adhesions were obviously suppressed on the composite surface, and the hemolysis in the blood contacting with the composite surface in the circulations was reduced. It is reasonable to consider that introducing carbon nanofiber into the polyurethane matrix improved blood compatibility for the polyurethanes.