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Early use of PEPA dialyzer for light chains removal and for the recovery from myeloma cast nephropathy: A case report
Authors:Gabriele Donati  Fulvia Zappulo  Anna Laura Croci Chiocchini  Giorgia Comai  Elena Zamagni  Gaetano La Manna
Abstract:Chemotherapy and extracorporeal treatment reduce serum free light chains (FLCs) allowing the recovery of acute kidney injury (AKI) caused by myeloma cast nephropathy (MCN). We report the first case of recovery from AKI in a patient with MCN who underwent the removal of FLCs using the PEPA filter, with an undisclosed cut‐off, combined with chemotherapy for multiple myeloma (MM).
Keywords:Multiple myeloma  cast nephropathy  free light chains  dialysis  Bortezomib  PEPA (Poly Ester Polymer Alloy)
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