基于红外光强的数字微流控系统定位

基于介电润湿(EWOD)效应的数字微流控(DMF)系统是一种能够实现多个独立的微液滴控制的新兴技术。该技术具有芯片结构简单、控制方法易于实现、样品消耗小和无流体运动死区等优点。为了满足DMF系统液滴精准驱动与控制的迫切需求,提出了一种基于红外光强的DMF系统定位方法,该方法可以在驱动控制液滴的同时,实现无输入参数的液滴精准定位。进一步基于该定位方法,实现了DMF系统的反馈控制。最终实现了一套具备液滴驱动、定位和反馈功能的DMF控制系统。实验结果表明提出的方案有利于提高DMF系统应用的成功率和可靠性。在同样的芯片参数结构下,成功率提高了约38%。同时设计的控制系统可以为其他研究基于EWOD的DMF系统的研究团队提供一个可靠的自动化实验平台。

Position for Digital Microfluidic System Based on Infrared Light Intensity

The digital microfluidic(DMF)system based on electrowetting on dielectric(EWOD)effect is a new technology and can realize multiple independent micro-droplets control.The technology,which the advantages of simple chip structure,easy implementation of the control method,low sample consumption and no dead zone of fluid motion.In order to meet the urgent needs of precise driving and control of droplets in the DMF system,aposition method with the DMF system based on an infrared light intensity was achieved.This method can realize precise droplets position without input parameters while the droplets are driven and controlled.Based on this position method,the feedback control of the DMF system was realized.Finally,a DMF control system with functions of droplet driving,position and feedback was achieved.The experimental results show that the proposed scheme is helpful to improve the success rate and reliability of DMF system applications.Under the same chip parameter structure,the success rate is increased by about 38%.Further,the proposed control system can provide a reliable automatic experimental platform for other research teams who focus on the DMF system based on the EWOD.