Cytology of cervical chordoma in cerebrospinal fluid from a child. A case report |
| |
Authors: | SZ Ali SB Semmelmeier C Urmacher |
| |
Affiliation: | Department of Laboratories, North Shore University Hospital-Cornell University Medical College, Manhasset, New York 11030, USA. |
| |
Abstract: | The cytologic findings on cerebrospinal fluid examination of cervical chordoma in a 2-year-old girl are presented. The major cell type was a small, isolated, hyperchromatic cell with sharply defined nuclear membrane and granular cytoplasm. However, the characteristic cell of this neoplasm, the so-called physaliferous cell with typical bubbly cytoplasm, was also noted. Cytologic findings were compared to biopsy findings, with a good correlation of tumor morphology. Clinical follow-up revealed unusually aggressive tumor behavior, and the patient died a year later despite intensive chemotherapy. The differential diagnosis of the condition is also discussed. |
| |
Keywords: | |
本文献已被 PubMed 等数据库收录! |
|