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Verapamil and mild hyperkalemia in hemodialysis patients: a potentially hazardous association
Authors:Letavernier Emmanuel  Couzi Lionel  Delmas Yahsou  Moreau Karine  Murcott Olivier  de Précigout Valérie
Affiliation:Service de néphrologie et d'hémodialyse, CHU Pellegrin, Bordeaux, France. letavernieremmanuel@yahoo.fr
Abstract:During the past 3 years, 3 patients undergoing intermittent hemodialysis (or about to do so) in our hospital developed a third-degree atrioventricular block while being treated with verapamil for blood pressure or supraventricular arrhythmia. In the 3 cases, mild hyperkalemia was concomitant. The medical history of these patients revealed no intrinsic cause of atrioventricular conduction disturbance. We report herein the 3 cases and draw attention to the risks of atrioventricular block in this particular context.
Keywords:Atrioventricular conduction  hemodialysis  hyperkalemia  K(+)(ATP) channels  verapamil
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