| 2,4-戊二酮缩甘氨酸席夫碱及其配合物的抑菌活性和量化计算 |
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| 引用本文： | 王瑾玲,郁铭,杨云,张姝明,丁峰,缪方明,杨静武. 2,4-戊二酮缩甘氨酸席夫碱及其配合物的抑菌活性和量化计算[J]. 计算机与应用化学, 2002, 19(3): 328-331 |
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| 作者姓名： | 王瑾玲 郁铭 杨云 张姝明 丁峰 缪方明 杨静武 |
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| 作者单位： | 1. 天津师范大学晶体化学研究所,天津,300074
2. 天津南开中学,天津,300102 |
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| 基金项目： | 天津市自然基金(003601711) |
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| 摘 要： | 采用文献方法合成了2，4－戊二酮缩甘氨酸席夫碱及其过渡金属配合物，进行了结构表征，利用单片纸碟法测定了它们对革兰氏阴性菌和阳性菌的抑制活性；利用MOPAC软件中的PM3程序对2，4－戊二酮、甘氨酸和2，4－戊二酮缩甘氨酸席夫碱进行了量化计算，量化计算结果与抑菌活性测定结果基本相符。
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| 关 键 词： | 2 4－戊二酮缩甘氨酸席夫碱 配合物 抑菌活性 抗癌药物 量子化学计算 |
| 文章编号： | 1001-4160(2002)03-328-331 |
| 修稿时间： | 2001-07-10 |
The Antibacterial Activities and Quantumn Chemistry Calculation of 2, 4 - Acetvlacetone Glycine Schiff Base and its Comulexes |
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| WANG Jin-ling,YU Ming,YANG Yun,ZHANG Shu-ming,DING Feng,MIAO Fang-ming,YANG Jing-wu. The Antibacterial Activities and Quantumn Chemistry Calculation of 2, 4 - Acetvlacetone Glycine Schiff Base and its Comulexes[J]. Computers and Applied Chemistry, 2002, 19(3): 328-331 |
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| Authors: | WANG Jin-ling YU Ming YANG Yun ZHANG Shu-ming DING Feng MIAO Fang-ming YANG Jing-wu |
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| Abstract: | 2,4- acetylacetone glycine Schiff base and its Complexes have been synthesized. The antibacterial activities have been determined by paper disk method. Theresult has been indicated that the complexes had more good inhibiting functionsthan the legand not only to Gram - positive bacterium but also to Gram - negativebacterium. PM3 program was used to perform quantum chemistry abinitiocalculation, the result of which coincides essentially with the antibacterialactivities. |
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| Keywords: | 2 4 - acetylacetone glycine schiff base complexes antibacterialactivities quantum chemistry calculation |
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