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用放射酶分析法研究补肾填精中药延缓鼠脑组织衰老的机理
引用本文:莫启忠,宫斌,黄欣,徐品初,王菊美,匡兴伟. 用放射酶分析法研究补肾填精中药延缓鼠脑组织衰老的机理[J]. 核技术, 1987, 0(10)
作者姓名:莫启忠  宫斌  黄欣  徐品初  王菊美  匡兴伟
作者单位:上海中医学院(莫启忠,宫斌,黄欣,徐品初,王菊美),上海中医学院(匡兴伟)
摘    要:雄性小鼠大脑线粒体单胺氧化酶(以下简称MAO)活性随鼠月龄增长明显升高。雌、雄性老年大鼠大脑和海马不同脑区MAO活性较青年对照组显著增加。补肾填精中药能明显地抑制老年小鼠和大鼠大脑及海马线粒体MAO活性,对机体脑组织产生明显延缓衰老的作用。

关 键 词:放射酶分析法  大脑  海马  线粒体  单胺氧化酶  补肾填精中药

Research on mechanism of anti-ageing of brain of mice and rats by traditional Chinese medicine of tonifying the kidney and tonifying the deficient essence with radiochemical method of enzyme assay
Mo Qizhong Gong Bin Huang Xin Xu PingchuWang Jumei Kuang Xingwei. Research on mechanism of anti-ageing of brain of mice and rats by traditional Chinese medicine of tonifying the kidney and tonifying the deficient essence with radiochemical method of enzyme assay[J]. Nuclear Techniques, 1987, 0(10)
Authors:Mo Qizhong Gong Bin Huang Xin Xu PingchuWang Jumei Kuang Xingwei
Affiliation:Shanghai College of Traditional Chinese Medicine
Abstract:The activities of mitochondrial monoamine oxidase (MAO) in brain of mouse are obviously increase with monthly added age of mouse. The activities of mitochondrial MAO in cerebrum and hippocampus of old rats Cboth male and female) are much more higher than young one. The traditional Chinese medicine of tonifying the kidney and tonifying the deficient essence could obviously inhibit activities of mitochondrial MAO in cerebrum and hippocampus of old rats and mouse, so it could prolong life of brain of rats and mice.
Keywords:radiochemical method of enzyme assay cerebrum hippocampusmitochondria monoamine oxidase traditional Chinese medicine of tonifying the kidney and tonifying the deficient essence
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