| 钛表面制备羟基磷灰石/壳聚糖复合涂层研究 |
| |
| 引用本文： | 王英波,鲁雄,冯波,屈树新,翁杰,陈建敏.钛表面制备羟基磷灰石/壳聚糖复合涂层研究[J].无机材料学报,2008,23(6):1241-1245. |
| |
| 作者姓名： | 王英波 鲁雄 冯波 屈树新 翁杰 陈建敏 |
| |
| 作者单位： | 1. 西南交通大学材料先进技术教育部重点实验室, 材料科学与工程学院, 成都 610031; 2. 中国科学院兰州化学物理研究所,固体润滑国家重点实验室, 兰州 730000 |
| |
| 基金项目： | 高等学校博士学科点专项科研(新教师)基金，国家自然科学基金 |
| |
| 摘 要： | 通过原位水热合成和溶胶-凝胶浸提涂敷法在碱处理的钛表面制备了HA/CS复合涂层. 接触角检测表明碱处理使钛表面具有超亲水性.X射线衍射分析表明复合涂层成分为HA和CS, 各组分含量由热重分析确定. 用扫描电镜对复合涂层的形貌进行观察,发现不同HA含量的复合涂层具有不同的形貌. 通过培养成骨细胞考察了复合涂层的细胞相容性.Alamar Blue检测表明HA/CS复合涂层表面细胞粘附及增殖能力较好. ALP检测表明HA/CS复合涂层表面的细胞分化能力较好. 综合研究结果表明, 复合涂层有较好的细胞相容性.
|
| 关 键 词： | 溶胶-凝胶 羟基磷灰石 壳聚糖 复合涂层 |
| 收稿时间： | 2008-1-21 |
| 修稿时间： | 2008-5-24 |
Investigation of HA/chitosan Composite Coatings Prepared by Sol-Gel on Alkali Treated Titanium Surfaces |
| |
| WANG Ying-Bo,LU Xiong,FENG Bo,Qu Shu-Xin,WENG Jie,CHEN Jian-Min.Investigation of HA/chitosan Composite Coatings Prepared by Sol-Gel on Alkali Treated Titanium Surfaces[J].Journal of Inorganic Materials,2008,23(6):1241-1245. |
| |
| Authors: | WANG Ying-Bo LU Xiong FENG Bo Qu Shu-Xin WENG Jie CHEN Jian-Min |
| |
| Affiliation: | 1. Key Lab of Advanced Technologies of Materials, Ministry of Education, School of Materials Science and Engineering, Southwest Jiaotong University, Chengdu 610031, China; 2. State Key Laboratory of Solid Lubrication, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000, China |
| |
| Abstract: | Hydroxyapatite/chitosan (HA/CS) composite coatings were prepared on titanium surfaces by hydro-thermal synthesis and Sol-Gel method. The composition, structure, morphology and biocompatibility of composite coatings were characterized. Ti surfaces are convertedinto super-hydrophilic surfaces by alkali treatment, XRD analysis reveals that the coatings are mainly composed of HA and CS and their compositions are determined by TG analysis. SEM observation shows that the coatings with different HA content have different morphologies. Osteoblasts are cultured on the coatings to evaluate their biocompatibility. Alamar Blue assay indicates that cells on the composite coatings has larger proliferation rate than those on pure titanium. Also the ALP activity of the cells on the composite coatings is higher than that on the pure titanium samples. The results demonstrate that as-prepared HA/CS composite coatings have good biocompatibility. |
| |
| Keywords: | Sol-Gel hydroxyapatite chitosan composite coatings |
| 本文献已被 维普 万方数据 等数据库收录！ |
| 点击此处可从《无机材料学报》浏览原始摘要信息 |
|
点击此处可从《无机材料学报》下载全文 |
|
