A disposable single-use electrochemical sensor for the detection of uric acid in human whole blood |
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Authors: | J-C H-H C-T D-M AS J-M |
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Affiliation: | Department of Chemistry, National Chung Hsing University, Taichung 402, Taiwan |
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Abstract: | We report here a non-enzymatic detecting electrode strip for fast monitoring of uric acid in human whole blood. A single-use amperometric uric acid sensor strip, incorporating a three-electrode configuration, has been fabricated on a polypropylene substrate using low cost screen-printing (thick-film) technology. Both the working and counter electrodes were prepared by screen-printing commercial carbon ink. The integration on the same support of pseudo-reference electrode was obtained by screen-printing a commercial silver ink and subsequent electrochemical pretreatment. Simply by placing a 20 μl human whole blood drop on the strip is enough for uric acid analysis by square-wave voltammetry. Real human whole blood samples were analyzed by this method and compared to the phosphotungstic acid clinical test procedure with satisfactory results. |
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Keywords: | Screen-printed electrode Single-use electrochemical sensor Uric acid Whole blood Electrochemical test strip |
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