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搅拌生物反应器的结构模型、放大及搅拌器改型
引用本文:赵学明.搅拌生物反应器的结构模型、放大及搅拌器改型[J].化学反应工程与工艺,1996,12(1):80-90.
作者姓名:赵学明
作者单位:天津大学化工系
摘    要:搅拌生物反应器(StirredBioreactor-SBR)是最重要的生物反应器,随着生物高新技术的发展,在医药、食品、化工及环境等领域对其提出了更高的要求。为此详细评述了最近10年在SBR的结构模型、放大及搅拌器改型方面的进展及存在的问题,特别强调了SBR性能研究的总体战略及具体的方法步骤。还就本学科发展的研究工作提出了建议。

关 键 词:搅拌生物反应器,混合,结构模型,放大,搅拌器改型

STRUCTURED MODELLING ,SCALE-UP AND RETROFITTING OF STIRRED BIOREACTORS
Zhao Xueming.STRUCTURED MODELLING ,SCALE-UP AND RETROFITTING OF STIRRED BIOREACTORS[J].Chemical Reaction Engineering and Technology,1996,12(1):80-90.
Authors:Zhao Xueming
Abstract:Stirred bioreactor is the most import ant type of bioreactors for industrial prduction processes (animal cells, plant cells and microbial cells culture). With the development of biotechnology, successful scale-up and the definition of optimal operating conditions of stirred bioreactors are still major problems. In this paper, the advances and problems in the structured modelling, scale-up and retrofitting of stirred bioreactors have been critically reviewed. The integrating strategies and the methodology in bioreactor performance studies have been stressed.Recommendations for further work have been made.
Keywords:Stirred bioreactors  Mixing  Structured modelling  Scale-up  Retrofitting  
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