| Y_2O_3对激光熔覆钛基复合涂层生物性能的影响 |
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| 引用本文： | 郑 敏,方 奥,刘其斌,樊 丁,张建斌.Y_2O_3对激光熔覆钛基复合涂层生物性能的影响[J].稀有金属材料与工程,2015,44(11):2817-2820. |
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| 作者姓名： | 郑 敏 方 奥 刘其斌 樊 丁 张建斌 |
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| 作者单位： | 兰州理工大学 机电工程学院，甘肃 兰州 730050,兰州理工大学 机电工程学院，甘肃 兰州 730050,贵州大学，贵州 贵阳 550003,兰州理工大学 甘肃省有色金属新材料省部共建国家重点实验室，甘肃 兰州 730050,兰州理工大学 甘肃省有色金属新材料省部共建国家重点实验室，甘肃 兰州 730050 |
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| 基金项目： | 兰州理工大学博士基金（0902ZXC116） |
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| 摘 要： | 采用激光熔覆技术在Ti-6Al-4V基材表面制备了生物陶瓷复合涂层。利用急性毒性实验、动物体内埋植实验以及体外细胞培养实验对钛基生物陶瓷复合涂层的生物性能进行了研究。结果表明:添加0.6%(质量分数)Y_2O_3的预置粉末和激光熔覆后的生物陶瓷涂层均无明显的急性毒性反应;动物体内分别埋植45、180 d后,与未添加稀土氧化物的复合涂层相比较,添加0.6%Y_2O_3的激光熔覆生物陶瓷复合涂层具有更好的骨小梁生成能力,且细胞在其表面生长良好;添加0.6%Y_2O_3的激光熔覆生物陶瓷复合涂层具备良好的生物相容性。
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| 关 键 词： | 激光熔覆 稀土 生物陶瓷 生物相容性 |
| 收稿时间： | 2014/11/8 0:00:00 |
Effect of Y2O3 on Biologic Performance of Titanium Matrix Composite Coating by Laser Cladding |
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| Zheng Min,Fang Ao,Liu Qibin,Fan Ding and Zhang Jianbin.Effect of Y2O3 on Biologic Performance of Titanium Matrix Composite Coating by Laser Cladding[J].Rare Metal Materials and Engineering,2015,44(11):2817-2820. |
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| Authors: | Zheng Min Fang Ao Liu Qibin Fan Ding and Zhang Jianbin |
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| Affiliation: | School of Mechanical and Electronical Engineering, Lanzhou University of Technology, Lanzhou 730050, China,School of Mechanical and Electronical Engineering, Lanzhou University of Technology, Lanzhou 730050, China,Guizhou University, Guiyang 550003, China,State Key Laboratory of Gansu Advanced Non-ferrous Metal Materials, Lanzhou University of Technology, Lanzhou 730050, China and State Key Laboratory of Gansu Advanced Non-ferrous Metal Materials, Lanzhou University of Technology, Lanzhou 730050, China |
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| Abstract: | The bioceramic composite coating was fabricated on the surface of Ti-6Al-4V matrix by laser cladding. And the biologic performance of bioceramic composite coating on titanium matrix was studied by acute toxicity testing, embedding test of animal in vivo and cell incubation test in vitro. The results show that the pre-placed powders with 0.6% Y2O3 and the laser-cladded bioceramic coating of 0.6% Y2O3 have no obvious acute toxicity reaction. The test in vivo (45 d, 180 d) and in vitro reveals that the laser-cladded bioceramic coating of 0.6% Y2O3 possesses better formation ability of trabecular bone than the laser-cladded bioceramic coating without rare earth. And the cells grow well on their surface. Therefore, the laser-cladded bioceramic coating of rare earth oxide Y2O3 is of excellent biocompatibility. |
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| Keywords: | laser cladding rare earth bioceramic biocompatibility |
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