Optimization of an herbicide release from ethylcellulose microspheres |
| |
Authors: | Zineb Elbahri Jean Louis Taverdet |
| |
Affiliation: | (1) Laboratoire Chimie et Environnement, Faculté des sciences et techniques, 23 rue Paul Michelon, 42032 Saint-Etienne Cedex 2, France |
| |
Abstract: | Summary The herbicide 2,4-D was microencapsulated using ethyl cellulose to develop controlled release formulations that protect it from photodegradation and evaporation and to reduce the environment pollution. Ethyl cellulose microspheres loaded with 2,4-D were prepared by the emulsion solvent-evaporation technique. We have obtained the desired microspheres with higher drug entrapment and encapsulation yield by varying certain conditions as stirring speed, polymer-solvent ratio, drug-polymer ratio, pH of continuous phase and organic phase solvent. The shape and size of microspheres were analysed by scanning electron microscopy. The herbicide release was studied at 25 °C and the release data were analysed according to Fick’s Law. The results demonstrate that we can control the release rate by modifying the process parameters. |
| |
Keywords: | |
本文献已被 SpringerLink 等数据库收录! |
|