真实人体呼吸道湍流仿真方法分析

计算流体力学被广泛用于可吸入药物在真实人体呼吸道区域沉积的研究,但存在计算效率不高的难点,无法满足临床应用所需。通过使用全结构化网格划分支气管树,应用k-ω SST、Transition SST、RSM-SSG和LES等湍流模型求解真实人体呼吸道流场,并与实验测量结果对比,验证不同湍流模型在计算真实人体呼吸道流场中的差异。在节约计算时间的同时,提出一套适合真实人体呼吸道模拟的快速且精确的流场仿真方法,并发现RSM-SSG湍流模型的计算结果与实验结果最为接近,为呼吸道计算流体力学仿真模拟的临床应用提供参考和依据。

Analysis of Turbulent Simulation Method of Realistic Human Respiratory Airway

Computational fluid dynamics is widely being used in the study of the deposition of inhaled drug particles in the respiratory airway. However, due to the low computational efficiency, it can hardly meet the requirement of clinical applications. Respiratory airways are meshed by fully structured mesh. Various turbulence models (e.g. k-ω SST, Transition SST, RSM-SSG, and LES) are applied to solve the flow field. Compared with experimental measurement, limitations and accuracy of different turbulence models on solving the flow field of the airway are analyzed. Finally, a rapid and accurate simulation method is summarized while reducing the time of the simulation. It is found that the RSM-SSG turbulence model can provide the most promising results compared with experimental data, which will lay a good foundation for the clinical application of computational fluid dynamics of the respiratory airways.