填充床固态发酵生物反应器模拟研究进展

数学模型是固态发酵生物反应器设计、优化和操作的重要工具,它不仅可以指导SSF过程生物反应器的设计和操作,而且可以深入分析发酵系统内的各种现象从而控制整个发酵过程。文章分析近几年固态发酵填充床生物反应器的拟均相假设模拟模型、非均相假设模拟模型和间歇混合填充床生物反应器模拟模型,对模拟结果进行讨论,深入分析如何用数学方法描述SSF系统的传热传质模型。在分析填充床固态发酵底物床层的系统组成及其性质的基础上,提出利用多孔介质体积平均理论研究SSF系统传热传质过程的可能性。

Review of recent developments in modeling of packed-bed solid-state fermentation bioreactors

Mathematical models are important tools for optimizing the design and operation of solid-state fermentation(SSF) bioreactors.Not only can models guide the design and operation of bioreactors but they can also provide insights into how the various phenomena within the fermentation system combine to control overall process performance.The current article evaluates the proposed models of Packed-Bed Solid-State Fermentation Bioreactors that hypothesis the substrate bed to be treated as a single pseudohomogeneous phase or nonpseudohomogeneous phase,and intermittently-mixed packed-bed bioreactors.The insights that have been achieved through the modeling work and the advances that have been made in heat and mass transportation models are discussed.In addition,the improvements of porous media volume averaging theory to heat and mass transportation models that will be necessary in the future are discussed.