香叶天竺葵鲜叶挥发油的镇咳活性成分分析

采用水蒸气蒸馏香叶天竺葵鲜叶,提取香叶油,并用GC-MS法对从香叶油中分离出的40多种组分做了分析,鉴定了其中24个化学组分,其GC含量占挥发油总量的95.45%含量最高的是香茅醇(30.69%),其它依次为甲酸香茅酯(11.89%)、异薄荷酮(9.73%)、β-古芸烯(6.89%)、芳樟醇(3.52%)、顺-玫瑰醚(3.38%)、大牛儿烯(3.13%)、香叶醇(3.05%)、α-石竹烯(2.55%)、α-蒎烯(2.43%)、β-石竹烯(2.31%)、α-二去氢菖蒲烯(2.21%)、β-榄香烯(2.19%)、丙酸香茅酯(2.08%)等。研究结果还表明,香叶油含有13.89%镇咳平喘药用功效的成分,如香叶醇、石竹烯、α-蒎烯、α-水芹烯、愈创木醇、β-月桂烯、柠檬烯等。本研究为香叶油的利用开拓了思路,也为其药用价值提供了初步的实验依据。

Analysis of the Active Ingredients of Geranium Oil Extracted from Fresh Leaves of Pelargonium Graveolens L.for Relieving Cough

A steam distillation process was adopted to extract geranium oil from fresh leaves of Pelargonium Graveolens L.. More than 40 ingredients were isolated from the geranium oil and 24 compenents of (those were identified by GC-MS.The GC content of 24 compenents were 95.45% of total essential oil. Among the ingredients, citronellol occupies the largest percentage(30.69%), which is followed successively by citronellyl formate(11.89%), isomenthone(9.73%), β-gurjunene(6.89%), linalool(3.52%), cis-rose oxide(3.38%), germacrene(3.13%), geraniol(3.05%), α-caryophyllene(2.55%), α-pinene(2.43%), β-caryophyllene(2.31%), α-calacorene(2.21%), β-elemene(2.19%), citronellyl propionate(2.08%), etc. The result also indicates that the geranium oil contains 13.89% of cough/asthma-relieving active ingredients such as geraniol, caryophyllene, α-pinene, α-phellandrene, guaiol, β-myrcene and limonene. This study has explored a new direction for further researches on geranium oil and provides preliminary experimental basis for developing its medicinal value.