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Cellular toxicity of carbon-based nanomaterials
Authors:Magrez Arnaud  Kasas Sandor  Salicio Valérie  Pasquier Nathalie  Seo Jin Won  Celio Marco  Catsicas Stefan  Schwaller Beat  Forró Laszló
Affiliation:Institut de Physique de la Matière Complexe (IPMC), Ecole Polytechnique Fédérale de Lausanne, 1015 Lausanne, Switzerland. arnaud.magrez@epfl.ch
Abstract:The cellular toxicity of carbon-based nanomaterials was studied as a function of their aspect ratio and surface chemistry. These structures were multiwalled carbon nanotubes, carbon nanofibers, and carbon nanoparticles. Their toxicity was tested in vitro on lung tumor cells. Our work clearly indicated that these materials are toxic while the hazardous effect is size-dependent. Moreover, cytotoxicity is enhanced when the surface of the particles is functionalized after an acid treatment.
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