Localization of the cellular expression of inhibin in trophoblastic tissue |
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Authors: | WG McCluggage P Ashe H McBride P Maxwell JM Sloan |
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Affiliation: | Spinal Pathology Unit Hospital Julio C. Perrando, Monteagudo, Resistencia, Argentina. |
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Abstract: | We report four new cases of chordoma of "the mobile spine", all at the L2 level. Diagnosis was often delayed due to predominantly nonspecific low back symptoms; however, neurological involvement is more frequent than in chordoma with a sacrococcygeal localization. No pathognomonic images have been described for any imaging modality, and differential diagnosis should include metastases, chondrosarcoma, and giant-cell tumor. Histopathological analysis can be performed on CT-guided puncture biopsy samples, but a high level of suspicion must be present and, if there is any doubt, immunohistochemical studies should be carried out. Despite being the treatment of choice, complete tumor resection by a double-approach spondylectomy is barely feasible at the L2 level. |
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