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Unlocking the potential of olive residues for functional purposes: update on human intervention trials with health and cosmetic products
Authors:Emily P Laveriano-Santos  Anna Vallverdú-Queralt  Rajeev Bhat  Anna Tresserra-Rimbau  Eulàlia Gutiérrez-Alcalde  Francesc M Campins-Machado  Rosa M Lamuela-Raventós  Maria Pérez
Affiliation:1. Polyphenol Research Group, Department of Nutrition, Food Science and Gastronomy, Faculty of Pharmacy and Food Sciences, Institute of Nutrition and Food Safety (INSA-UB), University of Barcelona, Barcelona, Spain

CIBER Physiopathology of Obesity and Nutrition (CIBEROBN), Institute of Health Carlos III, Madrid, Spain;2. ERA-Chair for Food (By-)Products Valorization Technologies (VALORTECH), Estonian University of Life Sciences, Tartu, Estonia;3. Polyphenol Research Group, Department of Nutrition, Food Science and Gastronomy, Faculty of Pharmacy and Food Sciences, Institute of Nutrition and Food Safety (INSA-UB), University of Barcelona, Barcelona, Spain

Abstract:Olive mill waste (OMW) is a promising source of valuable compounds such as polyphenols, terpenes, sterols, and other bioactive compounds, which are of interest to the pharmaceuticals and cosmeceutical industries. This review examines the potential of OMW extracts for health and beauty applications based on evidence reports from human clinical trials. The results achieved to date indicate health-enhancing properties, but little is known about the underlying mechanisms of action, dose–response relationships, and long-term impacts. Therefore, while olive by-products, extracted using eco-friendly methods, present opportunities for the development of high-value health and cosmetic products, further studies are necessary to determine the full range of their effects and establish specific therapeutic strategies. © 2024 The Authors. Journal of The Science of Food and Agriculture published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.
Keywords:bioactive compounds  olive oil by-products  waste reuse  circular economy  olive oil production  green technologies
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