乳腺癌前哨淋巴结不同检测方法效果研究

目的 :研究染色法、同位素法、联合法3种不同检测方法对乳腺癌前哨淋巴结检测的影响。方法:选取2007年9月²013年11月在我院就诊的早期女性乳腺癌患者为研究对象,将患者随机分为3组,蓝染料组、核素组、联合组。比较各组乳腺癌前哨淋巴结活检的成功率、准确率及假阴性率。结果 :与单纯使用染料的方法相比,联合法的假阴性率显著性降低,差异有统计学意义。与单用染料组及核素组相比,联合法发现的SLN数较多,但无统计学差异。结论:联合应用染料及同位素示踪较单一方法更能提高前哨淋巴结检测的成功率,降低假阴性率。

Research on the Effects of Different Test Methods for Sentinel Lymph Node（SLN） of Breast Cancer

Objective： To observe the effects of staining, isotopes and combined tests on Sentinel Lymph Node（SLN） of breast cancer.Methods： Picking women patients in our hospital with early breast cancer as study objects and randomly dividing them into 3 groups as blue dye, nuclide and combined ones to compare the success rates, accuracy rates and false negative rates of each group’s sentinel lymph node biopsy of breast cancer. Result： Compared with that of single dye usage, the combined test group showed a signiifcantly lower false negative rate; Compared with those of single dye usage and nuclide, the combined test group found more SLN number, yet without statistical differences.Conclusion： A combined application of dyes and isotopic tracing shows a better success rate of sentinel lymph node test and a lower false negative rate than single test.