Localizable imaging study for the noninvasive diagnosis of lesions with the backscattering polarized light

The asymmetry appearing in the degree of polarization (DOP) distribution of the backscattering polarized light from tissues is investigated by using polarized Monte Carlo simulation. When the incident point is close to the boundary of the lesion inside the tissue, high asymmetry emerges regardless of the polarized direction of the incident light. A noninvasive method based upon the DOP asymmetry of the backscattering light is proposed to locate lesions hidden in live tissues by scanning a point light source. Imaging of the front projection on complicated lesion structures is demonstrated with this method. Its transverse resolution, which is affected by the wavelength of incident light and the size of the scattering particle, can reach the diameter of the lesion scattering particle theoretically while the best longitudinal detection depth can be achieved by choosing a suitable incident wavelength according to the scattering characters of the tissue.